| Tom Cruise | Ethan Hunt |
| Dougray Scott | Sean Ambrose |
| Thandie Newton | Nyah Nordoff-Hall |
| Ving Rhames | Luther Stickell |
| Richard Roxburgh | Hugh Stamp |
| John Polson | Billy Baird |
| Brendan Gleeson | John C. McCloy |
| Rade Serbedzija | Dr. Nekhorvich |
| William Mapother | Wallis |
| Dominic Purcell | Ulrich |
| Director | John Woo |
| Producer | Terence Chang; Tom Cruise |
| Writer | Bruce Geller; Ronald D. Moore |
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