| Bill Murray | Steve Zissou |
| Owen Wilson | Ned Plimpton |
| Cate Blanchett | Jane Winslett-Richardson |
| Anjelica Huston | Eleanor Zissou |
| Willem Dafoe | Klaus Daimler |
| Jeff Goldblum | Alistair Hennessey |
| Michael Gambon | Oseary Drakoulias |
| Noah Taylor | Vladimir Wolodarsky |
| Bud Cort | Bill Ubell |
| Seu Jorge | Pelé dos Santos |
| Director | Wes Anderson |
| Producer | Wes Anderson; Dan Beers |
| Writer | Wes Anderson; Noah Baumbach |
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